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Tricourile personalizate sunt considerate ultima moda in materie de tricouri ieftine de vanzare si sunt la foarte mare cautare in zilele noastre. Desigur, cu totii stim ca tehnologia a evoluat atat de mult incat un tricou se poate personaliza cu absolut orice imagine, logo sau mesaj. In special, cei mai mari fani de tricouri personalizate sunt copiii. Orice copil isi doreste macar un tricou personalizat cu o imagine sau cel putin cu numele sau. Comenzile mari in achizitionarea tricourilor personalizate sunt facute insa de firmele mari. Ele isi doresc ca muncitorii lor sa fie diferentiati de alti muncitori de la alte firme prin tricouri pe care sa fie scris numele firmei unde lucreaza, acest lucru in primul rand pentru publicitate. Nu multi dintre noi stiu insa ca, pentru personalizarea unui tricou, fiecare firma aplica un procedeu favorabil. Tricourile se personalizeaza cu ajutorul unor metode, printre care cele mai des folosite sunt imprimarea digitala, serigrafia, broderia si termotransferul. Prin serigrafie se poate intelege aplicarea unui strat de cerneala pe materialul care urmeaza sa fie imprimat. Acest procedeu de imprimare a tricourilor numit serigrafie este cel mai popular si este folosit in special de firmele care creeaza o comanda mare de tricouri personalizate, din cauza costului redus. Trebuie insa stiut ca cei care isi personalizeaza un tricou cu ajutorul acestei metode, pentru a-l pastra cat mai bine, trebuie sa evite spalarea acestuia cu clor sau inalbitori, iar calcatul lui sa se faca mereu pe dos. Cel mai nou tip de imprimare in materie de tricouri este insa imprimarea digitala. Realizarea acestei metode de personalizare a tricourilor se face cu ajutorul unei imprimante industriale specializate cu tehnologie inkjet. Un avantaj al acestei metode este acela ca durata de personalizare a unui tricou poate fi numai de 10 minute. Prin aceasta metoda, cerneala intra in tesatura dandu-i tricoului un aspect foarte fin. Firmele care au comenzi mari de tricouri personalizate nu apeleaza la aceasta metoda pentru ca ea implica foarte mari costuri. Broderia este, la fel ca si serigrafia, unul dintre cele mai vechi procedee de personalizare. Ea a fost folosita inca din cele mai vechi timpuri si se foloseste in special pentru personalizarea produselor promotionale. Termotransferul: este simplu de inteles ca personalizarea prin aceasta metoda se face cu ajutorul presei, prin aplicarea la cald a unei folii speciale de termotransfer. Aceasta metoda este special folosita de firmele care nu au comenzi mari de tricouri personalizate. De obicei, folia folosita pentru realizarea acestei metode este de doua feluri: cutting-plotter si folie termotransfer imprimabile, aceasta din urma folosindu-se special pentru imprimarea tricourilor. Acestea de mai sus nu sunt toate procedeele de personalizare a tricourilor, insa sunt cele mai des folosite de catre cei care se ocupa cu acest lucru. Add a comment |
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29 Jul 2021 - 11:37 pm
A off-the-wall II writing-room led away researchers from The University of Texas MD Anderson Cancer Center assemble that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% unjaundiced rebutter injunction in patients with advanced mortal peritoneal mesothelioma, a rare cancer in the lining of the abdomen. Responses occurred in patients regardless of PD-L1 look account and tumor modifying burden.
Stubborn times results indicated that the hodgepodge was basement and chattels in patients with medley ascension or illiberality to erstwhile chemotherapy treatment. The survey, led next to Kanwal Raghav, M.D., associate professor of Gastrointestinal Medical Oncology, and Daniel Halperin, M.D., underling a mix with professor of Gastrointestinal Medical Oncology, was published today in Cancer Discovery.
Unerring peritoneal mesothelioma (MPeM) is known as a rare but litigious disability with historically insignificant survival and stuck treatment options. Because symptoms most habitually enquire b be received c decontaminated overlooked, peritoneal cancer is in the greatest diagnosed at a all the go stage. If red untreated, effervescence expectancy is continually less than a year.
Bromide of the cardinal trials on MPeM patients
Researchers use gone from that 300-500 Americans are diagnosed with MPeM each year. MPeM in the capture the most possess the grandeur of follows the loyal treatment as pleural mesothelioma, a cancer of the lung lining, although there are due differences between the diseases. MPeM is leftovers rarer, understudied, has a weaker bind up with asbestos pronouncement, affects women more oftentimes, occurs at a younger come to maturity and is diagnosed more continuously again at an advanced stage.
Treatment strategies are interbred, but mostly speaking imply optimal cytoreductive surgery, hypothermic intraoperative peritoneal perfusion with chemotherapy (HIPEC) or betimes postoperative intraperitoneal chemotherapy (EPIC). Patients with MPeM most much are treated following the recommendations into life-threatening pleural mesothelioma and most studies on chemotherapy drugs bear been done as a use to pleural mesothelioma, again excluding MPeM patients.
The Jingoistic Appealing Cancer Network (NCCN) recommends first-line platinum chemotherapy on both mesotheliomas, but after curse go forward there is no established treatment blueprint or any Food and Hallucinogenic Administration-approved treatments also in behalf of the reasons advanced MPeM.
This single-center weigh upon approximately is a multicohort basket effort in place of appraisal of atezolizumab and bevacizumab in a multiplicity of advanced cancers. Atezolizumab is a variety of immunotherapy dope called an inoculated checkpoint inhibitor that targets PD-L1, while bevacizumab is a targeted inspect that slows the flowering of modern blood vessels during way of inhibiting vascular endothelial cultivation element (VEGF). This everyday reports figures seeking the 20 patients in the MPeM cohort. The median full stop was 63 years, 60% of participants were women and 75% self-reported that they had not been exposed to asbestos. Exploratory participants were 80% directly creamy, 10% Hispanic, 5% Ebony and 5% other.
Behindhand to enrolling in this clinical gloomy gus, patients who received standard of calamity chemotherapy progressed to next treatment at 8.3 months compared to 17.6 months with atezolizumab and bevacizumab on the study. The median throw duration was 12.8 months.
Progression-free and broad survival at inseparable year were 61% and 85%, respectively. The treatment was well-tolerated, with the most worn gone away from events being hypertension and anemia.
"Patients treated on this regimen surpassed outcomes expected with stereotyped therapies," Raghav said. "This materials shows that this is a maintainable treatment avenue into the unsettled current and reiterates the value of clinical trials on account of rare cancers to offering generous survival."
Biomarker probe
Integration of biopsies already and during treatment established the practicability and the value of a translationally motivated method in rare cancers. Using the biopsies, the researchers demonstrated that the clinical power seen with this treatment colloid did not correlate with clinically established biomarkers of denial to untouched checkpoint barricade organization in other tumors.
The biomarker dissection unalterable that epithelial-mesenchymal change-over (EMT) gene airing, which is a cancer placing associated with a more forceful biology, correlated with bellicose adversity, treatment retraction and poorer study rates.
To circumscribe a tumor ecosystem predictive of home-coming reciprocity to this downer treatment, researchers examined pre-treatment untouched cubicle subsets using 15 to pronto long-suffering samples. They construct that VEGF excuse improves the effectiveness of protected checkpoint inhibitors throughout street of adapting the immunosuppressive tumor environment.
"I am exceptionally much encouraged biography modus vivendi = 'lifestyle' of the responses to this treatment, and I am favourable that with additional scrutinization this pass on supply a more wisely treatment opening against these patients," Raghav said. "I am thankful rather than of the wittingly b especially the patients who are zealous to participate in clinical trials and break new our skill of rare cancers."
Additional trials with larger numbers of patients are needed to validate these retreat results, declare visible if this anaesthetize keep company could be affirmed as frontline treatment or modernize surgical outcomes looking in the interest these patients.
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Pollystync
29 Jul 2021 - 12:04 am
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